Immunologically active phenotype is associated with response to PD-1/PD-L1 inhibitors in patients with advanced non-small cell lung cancer

ABSTRACT: Immunotherapy in immunologically active tumors may improve prognosis of non-small cell lung carcinomas (NSCLC). Our objective was to develop a reliable and stable scoring system for the identification of immunologically active HNSCC and to evaluate its association with response to immunotherapies. A Hot Oral Tumor (HOT) score was developed using data from The Cancer Genome Atlas in human-papillomavirus negative head and neck squamous cell carcinomas; it was computed in 92 patients with early stage NSCLC treated with surgery to evaluate the prognostic impact of the HOT score.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162520 | GEO | 2022/07/07

REPOSITORIES: GEO