Single cell RNA-seq of brain glioblastoma samples

ABSTRACT: Glioblastomas (GBM) are the most aggressive type of brain tumors with a dismal prognosis. The effectiveness of anti-tumor drugs is thwarted by brain endothelial cells (ECs) in the tumor microenvironment. However, the characteristics of ECs remains poorly inventoried at the single-cell level. We performed single-cell RNA sequencing (scRNA-seq) for ECs from 4 GBMs and matching non-malignant brain samples, and identified distinct EC phenotypes in GBM.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162631 | GEO | 2021/07/08

REPOSITORIES: GEO