Reduced Physical Activity Alters the Leucine-Stimulated Translatome in Aged Skeletal Muscle

ABSTRACT: Background: Periods of inactivity experienced by older adults induce nutrient anabolic resistance creating a cascade of skeletal muscle transcriptional and translational aberrations contributing to muscle dysfunction. Objective: To identify how inactivity alters leucine-stimulated translation of molecules and pathways within the skeletal muscle of older adults.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162730 | GEO | 2020/12/06

REPOSITORIES: GEO