Adult T-cells impair neonatal cardiac regeneration 

ABSTRACT: Neonate mice and men display a transient cardiac regenerative potential that rapidly declines postnatally. Thus, patients that survive a myocardial infarction (MI) often develop chronic heart failure (HF) as a consequence of this poor myocardial healing capacity. Herein, we hypothesized that the cardiac “regenerative-to-scarring” transition is driven by the developing adaptive immune system.

ORGANISM(S): Mus musculus

PROVIDER: GSE163277 | GEO | 2023/01/03

REPOSITORIES: GEO