FFPE-ATAC decodes the chromatin accessibility from the clinical archived FFPE tissues

ABSTRACT: We present FFPE-ATAC, a new ATAC-seq tool for chromatin accessibility profiling that decodes the chromatin accessibility from mouse FFPE tissue and clinical archived FFPE tissues. The FFPE-ATAC generates the high-quality chromatin accessibility profiles from clinical FFPE tissue sections with 5-20 µm thickness, and reveals the disease-associated regulatory elements in different types of FFPE archived tissue. FFPE-ATAC enables to decode the chromatin states regulating the gene regulation in the cancer and understand the epigenetic regulation in the translational studies.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE163306 | GEO | 2021/06/30

REPOSITORIES: GEO