Terminally differentiated CD4+ T cells promote myocardial inflammaging

ABSTRACT: We generated a xenograft transplantation model in which young humanized mice were treated to harbor a senescent-like human CD4+ T cell compartment. Our data uncover a role for terminally differentiated T cells in promoting cardiac inflammaging.

ORGANISM(S): Mus musculus

PROVIDER: GSE163413 | GEO | 2021/02/15

REPOSITORIES: GEO