Developmental programs in childhood neuroblastoma [scRNA-seq SK-N-AS]

ABSTRACT: Neuroblastoma is a pediatric tumor of the developing sympathetic nervous system. We investigate the developmental origin of neuroblastoma, the role of oncogenic MYCN in blocking normal differentiation and evaluate therapeutic interventions to overcome differentiation blocks. Here, we provide single cell expression profiles (scRNA-seq MARS-seq) of SK-N-AS cells (n=603).

ORGANISM(S): Homo sapiens

PROVIDER: GSE163430 | GEO | 2020/12/18

REPOSITORIES: GEO