BET inhibitors enhance the expression of fetal and embryonic hemoglobin genes [K562]

ABSTRACT: We performed RNA-sequencing on erythroid cell lines treated with DMSO or JQ1. We found that JQ1 induces erythropoiesis and specifically upregulated fetal and embryonic globin genes at the beta globin locus.

ORGANISM(S): Homo sapiens

PROVIDER: GSE163594 | GEO | 2021/12/01

REPOSITORIES: GEO