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10X-single cell seq of B cells during colitis (d0 and d14)

ABSTRACT: B cells expand during the recovery after DSS-induced colonic inflammation. To investigate if a specific subtype is expanding and to analyse the transcriptional profile of these cells a transcriptional analysis on single cell level was carried out. In detail, B cells were isolated from the colon of mice on day 0 (no treatment) or day 14 (recovery) after 7 days of DSS treatment by flow cytometric sorting and analyzed by 10X sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE163637 | GEO | 2021/12/06

REPOSITORIES: GEO

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10X-single cell seq of IEC and Stroma during recovery after DSS colitis in B cell sufficient/deficient mice

Project description:B cells expand during the recovery after DSS-induced colonic inflammation and might play a role in influencing tissue repair. To analyze the impact B cells might have on intestinal epithelial cells and stromal cells during recovery after intestinal injury the transcriptional profile of these mice was analysed in mice depleted of B cells and control mice on day 14 after DSS colitis.

2021-12-06 | GSE163638 | GEO

Genomic profile of dextran sulphate sodium-induced colitis model in rats

2008-11-01 | GSE9281 | GEO

Transcription profiling of rat dextran sulphate sodium-induced colitis model

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2008-11-13 | E-GEOD-9281 | biostudies-arrayexpress

Colon gene expression signatures in wild type and Card9-/-mice exposed to DSS induced colitis

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Small RNA Sequencing facilitates quantitative analysis of miRNA expression in feces from mice during DSS-induced colitis and the recovery phase

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10X-single cell seq of B cells during colitis (d0 and d14)

Project description:10X-single cell seq of B cells during colitis (d0 and d14)

| PRJNA686980 | ENA

mRNA transcriptome sequencing of wild type (WT) and intestinal epithelial cell specific Axin1 Knockout mice (Axin1KOΔIEC) that have udergone DSS-induced colitis and AOM/DSS-induced colorectal tumorigenesis

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2022-02-09 | GSE196220 | GEO

A functional genomics predictive network model identifies regulators of inflammatory bowel disease: Ribo-zero RNAseq mouse distal colon DSS Colitis model of genetically engineered mice

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2021-12-10 | GSE190595 | GEO

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