Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Frozen bone marrow (BM) samples belonging to pediatric acute myeloid leukemia (AML) cohort analyzed by Human Transcriptome Array 2.0 (HTA 2.0)

ABSTRACT: We analyzed 12 pediatric AML bone marrow RNA in order to determine the whole transcriptome expression levels by HTA 2.0 microarrays. Results provided insights into the regulation, at transcript level, of driver genes involved in primary chemiotherapy failure (after two cycles of Induction phase; blasts>5%).

ORGANISM(S): Homo sapiens

PROVIDER: GSE163643 | GEO | 2021/03/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Frozen bone marrow (BM) samples belonging to pediatric acute myeloid leukemia (AML) cohort analyzed by Human Transcriptome Array 2.0 (HTA 2.0)

Project description:Frozen bone marrow (BM) samples belonging to pediatric acute myeloid leukemia (AML) cohort analyzed by Human Transcriptome Array 2.0 (HTA 2.0)

| PRJNA686991 | ENA

Exon Level Expression Profiling:HTA 2.0 array

Project description:Exon Level Expression Profiling:HTA 2.0 array

| PRJNA814287 | ENA

Human Transcriptome Array 2.0 (HTA) from healthy colonic, colorectal adenoma and colorectal cancer tissue

Project description:Whole transcriptome expression levels of healthy colonic, colorectal adenoma and colorectal cancer biopsy samples were analyzed by HTA 2.0 microarrays

2019-09-13 | GSE100179 | GEO

Screening for potential target genes of microRNA-548ac using HTA 2.0 microarrays

Project description:We screened for target genes of hsa-miR-548ac by transcriptome profiling. The miRNA was overexpressed in HeLa cells by transient transfection of a precursor miRNA expression plasmid. High-density Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used for the gene expression analysis. This GEO entry provides the microarray data preprocessed according to the gene level workflow.

2018-10-03 | GSE120769 | GEO

Human Transcriptome Array 2.0 (HTA) in matched colorectal cancer and normal colonic mucosa.

Project description:We analyzed, by HTA 2.0, colorectal adenocarcinoma samples and matched normal colonic tissues in order to determine the whole transcriptome expression levels. Three widely used colorectal cancer cell lines were also analyzed. Results provided insights into the regulation, at transcript level, of genes involved in copper homeostasis.

2017-03-31 | GSE84984 | GEO

Human Transcriptome Array 2.0 (HTA) in matched colorectal cancer and normal colonic mucosa

2016-12-31 | GSE73360 | GEO

Comparison of Affymetrix and NuGEN amplification methods for HTA 2.0 microarray

Project description:Comparison of total RNA-seq and Affymetrix GeneChip(R) Human Transcriptome Array 2.0 analysis methods and Affymetrix GeneChip® WT PLUS Reagent and NuGEN Ovation® PICO WTA System V2 amplification methods for the detection of significant differentially expressed genes isolated from whole blood and brain RNA samples Affymetrix and NuGEN amplification methods are compared to determine which is most efficient, cost effective, and accurate in the detection of differentialy expressed transcript clusters on the HTA 2.0 microarray The optimum amplification microarray data is compared to total RNA-seq analysis of the same samples to determine which is the most efficient, cost effective, and accurate method of detecting differentially expressed genes

2020-09-30 | GSE120327 | GEO

Human Transcriptome Array 2.0 (HTA) from SW480 colon adenocarcinoma cells transfected with LINC00152 Stealth siRNAs or Stealth Negative Control Medium GC siRNAs

Project description:Whole transcriptome expression levels of SW480 colon adenocarcinoma cells transfected with LINC00152 Stealth siRNAs or Stealth Negative Control Medium GC siRNAs, analyzed by HTA 2.0 microarrays

2020-03-04 | GSE111413 | GEO

Comparison of Affymetrix and NuGEN amplification methods for HTA 2.0 microarray

Project description:Comparison of Affymetrix and NuGEN amplification methods for HTA 2.0 microarray

| PRJNA492492 | ENA

Transcriptome data of multiple sclerosis patients receiving fingolimod therapy [HTA-2_0, CD4+ cells, gene level]

Project description:We analyzed the gene expression patterns of different blood cell types before and during fingolimod treatment in a group of patients with relapsing-remitting multiple sclerosis (RRMS). Affymetrix Human Transcriptome Arrays (HTA) 2.0 were used to obtain gene expression profiles of immune cell populations from 10 RRMS patients within the first 3 months of fingolimod treatment. This GEO entry provides the Affymetrix HTA 2.0 microarray data of peripheral blood CD4+ cells, preprocessed according to the gene level workflow. EDTA blood samples were taken from all patients immediately before first and second fingolimod administration as well as after 3 months of therapy. Total RNA of CD4+ cells positively selected from each blood sample was extracted, labeled and hybridized to high-density Affymetrix HTA 2.0 microarrays to quantify the transcript levels.

2015-09-19 | E-GEOD-73079 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data