Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Wild type mouse lung control vs. high fat diet

ABSTRACT: To study the effects of a high fat diet on the mouse lung transcrptional profile.

ORGANISM(S): Mus musculus

PROVIDER: GSE16377 | GEO | 2010/06/01

SECONDARY ACCESSION(S): PRJNA116331

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

wild type mouse lung control vs. high fat diet

Project description:To study the effects of a high fat diet on the mouse lung transcriptional profile. 6 samples were analyzed. 3 wild type mice on a control diet (lung samples) vs. 3 wild type mice on a high fat diet (lung samples).

2010-06-08 | E-GEOD-16377 | biostudies-arrayexpress

Mouse muscle mitochondrial proteome changes in high fat diet vs. low fat diet

Project description:We investigated remodeling of the mitochondrial proteome to determine mechanisms of changes to lipid oxidation following high-fat feeding. C57BL/6J mice consumed either a high-fat diet (HFD, 60% fat) or low fat diet (LFD, 10% fat) for 12 weeks. Mice were fasted 4 hours then anaesthetized by sodium pentobarbital for tissue collection. A mitochondrial-enriched fraction was prepared from gastrocnemius muscles and underwent proteomic analysis by high-resolution mass spectrometry.

2018-04-12 | MSV000082272 | MassIVE

C57BL6/J livers exposed to low fat and high fat diet, wild-type vs Cyp1b1 null

2014-01-09 | GSE53910 | GEO

C57BL6/J livers exposed to low fat and high fat diet, wild-type vs Cyp1b1 null

Project description:Investigating the transcriptional changes in mouse livers exposed to low and high fat diets for 11 weeks. Determine what gene changes in the Cyp1b1 null livers may be contributing to prevention of increased adiposity when givin a high fat diet. Three Comparison experiment. Comparing wild-type low fat vs Cyp1b1 null low fat, wild-type high fat vs Cyp1b1 null high fat and low fat vs high in wild-type mice. Sample size is 3 per group. Limma analysis data provided in Series supplementary file (Normalized log2 ratio of (Cy3/Cy5) representing test group/control group).

2014-01-09 | E-GEOD-53910 | biostudies-arrayexpress

High-Fat-Diet

Project description:High Fat Diet Experiment SD rats fed either an AIN93G-based low fat diet or an AIN93G-based high fat diet. Keywords: ordered

2006-01-01 | GSE2226 | GEO

Serum proteomics of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet

Project description:The serum samples from wild type mice fed high-fat diet for 12 weeks (WT_Serum) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (KI_Serum) were mixed separately, and subjected to proteomic study by Label-free quantitative techniques and mass spectrometry-based proteomics techniques in Jingjie PTM BioLab (Hangzhou) Co. Ltd (www.ptm-biolab.com.cn). The difference was determined by 1.5-fold-change criterion, FDR < 0.01.

2022-08-11 | PXD034069 | Pride

The eWAT proteomics of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet

Project description:The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to proteomic study by Label-free quantitative techniques and mass spectrometry-based proteomics techniques, etc. The proteomics of mixed eWAT samples were performed in Jingjie PTM BioLab (Hangzhou) Co. Ltd (www.ptm-biolab.com.cn). The difference was determined by 1.5-fold-change criterion, FDR < 0.01.

2022-08-11 | PXD034074 | Pride

Quantitative analysis of standard diet and high fat diet-fed wild type and Sirt3 knockout mouse pancreatic islets transcriptomes.

Project description:To explore the underlying mechanism for the regulatory role of SIRT3 in pancreatic islets under standard and high fat diet feeding, we conducted RNA sequencing on the isolated islets from standard diet and high fat diet-fed wild type and pancreatic beta cell selective Sirt3 knockout mice (four groups in total). Three biological replicates were performed for each group.

2022-08-15 | GSE156345 | GEO

Gene expression Tet-mev-1 mouse fed either normal diet or high fat high sucrose diet compared with wild type mouse

Project description:To assess the effect of steatosis and oxidative stress on progression of liver fibrosis, we have employed whole genome microarray expression profiling as a discovery platform to identify genes that are related with oxidative stress- and steatosis-induced hepatic fibrogenesis. When wild type mice were fed high-fat/high-sucrose diet for 24 weeks, expression of 69 genes was changed more than 10-fold compared with wild type animals fed normal diet, 11 of which were categorized to lipid metabolic process. Moreover, expression of 208 genes showed more than 5-fold changes in Tet-mev-1 mice fed high-fat/high-sucrose diet compared with the same transgenic animals fed normal diet, and gene ontology analyses indicated significant changes in chemokine activity and chemokine receptor binding as well as defense and immune responses. oxidative stress and high fat high calorie induced gene expression in wild type or Tet-mev-1 mouse liver tissue. wild type and Tet-mev-1 mice were fed either normal diet or high fat high sucrose diet for 4 months, and have been given doxycycline-containing water from embryo. Each group were perfomed by duplicate.

2015-05-07 | E-GEOD-68632 | biostudies-arrayexpress

HIgh fat refined sugar diet and hippocampus

Project description:Rats were fed either a control diet or high fat and refined sugar (HFS) diet and hippocampus was resected for proteomic analysis

2012-09-14 | PXD000028 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data