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Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21

ABSTRACT: We reported a 3-month MR intervention alleviated age-related cognitive impairment. Here we present transcriptomics data of mice hippocampus to further investigate how MR regulates vital biological processes and pathways. After mapping clean RNA-seq reads of all mice against the Mus musculus genome, we detected 13,218 genes (including 3,187 new predicted genes with no annotation) with fragments per kilobase of transcripts per million mapped reads (FPKM) value. Gene set enrichment analysis (GSEA) was used for pathway or functional analysis of RNA-seq data.

ORGANISM(S): Mus musculus

PROVIDER: GSE164097 | GEO | 2021/12/31

REPOSITORIES: GEO

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Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21.

Project description: Not available

| S-EPMC8022247 | biostudies-literature

Contrasting patterns of expression divergence in early and late stages of population divergence in mice

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Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21

Project description:Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21

| PRJNA688895 | ENA

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