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Escherichia coli Tiling Array for In vivo Protein Occupancy Display

ABSTRACT: Using a high-density tiling array containing 25-mer oligonucleotides at the resolution of one every four base pairs across the entire genome, we developed In vivo Protein Occupancy Display (IPOD), a technology that reveals protein occupancy across an entire bacterial chromosome at the resolution of individual binding sites. Application to Escherichia coli reveals thousands of protein occupancy peaks, highly enriched within and in close proximity to non-coding regulatory regions.

ORGANISM(S): Escherichia coli

PROVIDER: GSE16414 | GEO | 2009/09/01

SECONDARY ACCESSION(S): PRJNA116353

REPOSITORIES: GEO

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