Gene expression data from endometrial cancer patient-derived cells (EDC-PDCs) treated with Efp siRNA

ABSTRACT: To examine the role of Efp in endometrial cancer, patient-derived cells were treated with siRNA targeting Efp (siEfp) or control siRNA (siControl). siRNA-mediated Efp silencing resulted in suppressed spheroid proliferation and altered gene expression profile, featuring downregulation of genes related to cell cycle and inflammation/immune responses. This study provides an insight into alternative endometrial cancer therapeutic strategies targeting Efp.

ORGANISM(S): Homo sapiens

PROVIDER: GSE164724 | GEO | 2024/01/13

REPOSITORIES: GEO