Local Translation in Nuclear Condensate Amyloid-bodies

ABSTRACT: We report that solid-like condensates Amyloid-bodies are hubs of stress-resistant local nuclear translation in cells responding to high temperature. RNA-seq. analysis of purified Amyloid-bodies confirms that HSF1-transcribed mRNAs accumulate in these solid-like condensates during stress.

ORGANISM(S): Homo sapiens

PROVIDER: GSE164846 | GEO | 2021/01/15

REPOSITORIES: GEO