Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma

ABSTRACT: We characterized the transcriptomes of both primary tumors and lung metastases tha developed in mice following deletion of Lats1 and Lats2 from Slc34a1-expressing cells as well as tumors arising from kidney allografts of and immortalized Lats1-/-;Lats2-/- cell line derived from the renal papilla.

ORGANISM(S): Mus musculus

PROVIDER: GSE164879 | GEO | 2021/01/15

REPOSITORIES: GEO