Gene expression analysis of single and co-cultured HER2 L755S mutants in MCF-10A background

ABSTRACT: PIK3CA E545K mutants induce epidermal growth-factor independent proliferation of HER2 L755S mutants through a contact-mediated mechanism. We used RT2 Profiler PCR Arrays to study changes in gene expression in the HER2 L755S mutants when co-cultured with the PIK3CA E545K mutants and compared it to the HER2 L755S mutants grown in isolation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE165150 | GEO | 2021/03/18

REPOSITORIES: GEO