RNA-seq Analysis of sibling and dhx38-- zebrafish

ABSTRACT: Purpose: Loss of dhx38 disrupts the proliferation and differentiation balance of hematopoiesis. Notably, the mitosis of both EMPs and HSPCs are blocked in the pre-metaphase with abnormal chromatin karyotype in the dhx38--zebrafish. RNA-seq analysis screened abnormal splicing and aberrant expression genes that are likely to explain the dysfunction of mitosis.

ORGANISM(S): Danio rerio

PROVIDER: GSE165203 | GEO | 2022/08/09

REPOSITORIES: GEO