Creatine mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer

ABSTRACT: Obesity is a major risk factor for adverse outcomes in breast cancer. Maguire, Ackerman et al. reveal Gatm and Acsbg1 as molecular regulators of obesity-driven breast cancer progression. They further show that in obesity creatine is a key metabolite in the crosstalk between adipocytes and breast tumors.

ORGANISM(S): Mus musculus

PROVIDER: GSE165273 | GEO | 2021/01/22

REPOSITORIES: GEO