Qualitative differences in diseases-associated mutants reveal molecular signatures and aberrant signaling-crosstalk

ABSTRACT: We generated HEK293 cells stably expressing diseases-derived mutants and performed a genome-wide transcriptome analysis using the 60K SurePrint G3 Human gene expression microarray technology. By the analysis of their gene expression profiles, we identified diseases-associated signature genes that may serve as diagnostic markers or therapeutic targets for the diseases.

ORGANISM(S): Homo sapiens

PROVIDER: GSE165823 | GEO | 2022/06/13

REPOSITORIES: GEO