Single cell RNA sequencing of CD41+ and CD41- CD34+ HPC in model of RUNX1 insufficiency

ABSTRACT: To gain insights into the global and local transcriptomic changes underlying defects in adult RUNX1in HSPCs, we then performed scRNA SEQ on sorted CD41a- and CD41a+ HSPCs from cultures expressing NT or RUNX1-targeting lentiviral shRNA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE166042 | GEO | 2021/05/19

REPOSITORIES: GEO