Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina NextSeq 500 (Mycobacterium tuberculosis)
ORGANISM(S): Mycobacterium tuberculosis
SUBMITTER: Eliza Peterson
PROVIDER: GSE166546 | GEO | 2021-12-15
REPOSITORIES: GEO
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NPJ systems biology and applications 20211206 1
The ability of Mycobacterium tuberculosis (Mtb) to adopt heterogeneous physiological states underlies its success in evading the immune system and tolerating antibiotic killing. Drug tolerant phenotypes are a major reason why the tuberculosis (TB) mortality rate is so high, with over 1.8 million deaths annually. To develop new TB therapeutics that better treat the infection (faster and more completely), a systems-level approach is needed to reveal the complexity of network-based adaptations of M ...[more]