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High throughput screening identifies microRNAs regulating PCSK9 and LDL receptor expression

ABSTRACT: Using a high throughput human microRNA library screen, we identified microRNAs targeting the 3’untranslated region of human PCSK9

ORGANISM(S): Homo sapiens

PROVIDER: GSE166680 | GEO | 2021/07/07

REPOSITORIES: GEO

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High throughput screening identifies microRNAs regulating PCSK9 and LDL receptor expression

Project description:High throughput screening identifies microRNAs regulating PCSK9 and LDL receptor expression

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In vivo adenine base editing of PCSK9 in mice and macaques reduces LDL-cholesterol levels [amplicon-seq]

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