Altered hippocampal transcriptome dynamics following sleep deprivation

ABSTRACT: Purpose: To comprehensively identify the gene expression changes that occur after acute sleep deprivation. Method: We performed total RNA sequencing after 5hours of sleep deprivation. Results: Using total RNA-sequencing, we show that acute sleep deprivation causes dramatic gene expression changes in the mouse hippocampus. Conclusion: This study provides insight into the biological impact of acute sleep deprivation.

ORGANISM(S): Mus musculus

PROVIDER: GSE166831 | GEO | 2021/03/01

REPOSITORIES: GEO