Genetic Signatures from RNA sequencing of Pediatric Localized Scleroderma (LS) Skin

ABSTRACT: In this study, we explored the initial results of RNA transcriptomic expression between pediatric localized scleroderma skin tissue and healthy control skin, with a subanalyses of transcriptomic expression in different disease states. LS gene signatures compared to healthy controls showed a distinct expression of an inflammatory response gene signature (IRGS) composed of IFNγ, IFNα and TNFα associated genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE166861 | GEO | 2021/06/12

REPOSITORIES: GEO