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Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells

ABSTRACT: Loss of Pten and inhibition of PI3K induced apoptosis of hematopoietic stem/progenitor cells upon endothelial to hematopoietic transition and surviving hematopoietic stem/progenitor cells committed to all blood lineages but displayed reduced stemness

ORGANISM(S): Danio rerio

PROVIDER: GSE166900 | GEO | 2021/02/17

REPOSITORIES: GEO

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Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells

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