Identification of JMJD1A and JMJD2B target genes in hypoxic colon carcinoma cells

ABSTRACT: The Hypoxia-Inducible Factors induce the expression of the histone demethylases JMJD1A (KDM3A) and JMJD2B (KDM4B), linking the hypoxic tumor microenvironment to epigenetic mechanisms that may foster tumor progression. This dataset includes expression data obtained from exposing colon carcinoma cells to hypoxia in combination with siRNA-mediated knockdown of the hypoxia-inducible histone demethylases JMJD1A and JMJD2B.

ORGANISM(S): Homo sapiens

PROVIDER: GSE166991 | GEO | 2021/11/03

REPOSITORIES: GEO