Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bulk RNA-seq of CRISPR SATB2 Knockout Human Colonic Organoids

ABSTRACT: To evaluate SATB2 function in human colonic epithelium, we knocked out the SATB2 gene in 3D cultured human colonic organoid.

ORGANISM(S): Homo sapiens

PROVIDER: GSE167285 | GEO | 2021/10/05

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Bulk RNA-seq of Mouse Colonic Organoids: SATB2 and FOXD2KO CRISPR Knockout

Project description:CRISPR knock out the Satb2 or Foxd2 gene from mouse colonic organoids to validate core human and mouse large intestine stem cell enrich TFs.

2021-10-05 | GSE167283 | GEO

Bulk RNA-seq of CRISPR SATB2 Knockout Human Colonic Organoids

Project description:Bulk RNA-seq of CRISPR SATB2 Knockout Human Colonic Organoids

| PRJNA704074 | ENA

Bulk RNA-seq of mouse colonic organoids: CRISPR functional Screening of Satb2-interact proteins (NuRD and SWI/SNF complex)

Project description:CRISPR knock out the NuRD and SWI/SNF complex gene from mouse colonic organoids to validate the potential function with SATB2.

2024-03-07 | GSE213878 | GEO

Bulk RNA-seq of Mouse Colonic Organoids: SATB2 and FOXD2KO CRISPR Knockout

Project description:Bulk RNA-seq of Mouse Colonic Organoids: SATB2 and FOXD2KO CRISPR Knockout

| PRJNA704069 | ENA

Bulk RNA-seq of Early Time Course Colonic Epithelia from Satb2-deficient and WT mice

Project description:Given that SATB2 is expressed in differentiated colonic cells as well as the stem cells, we evaluated whether SATB2 might directly regulate the identity of the differentiated cells

2021-10-05 | GSE180023 | GEO

ChIP-seq of Colonic Intestine Epithelium from Satb2-deficient and WT mice

Project description:We use ChIP-seq to understand the genomic binding sites of SATB2 in colonic epithelium and to study the shifting of CDX2 and HNF4A's genomic binding sites after SATB2 loss in colonic epithelium.

2021-10-05 | GSE167287 | GEO

CUT&RUN Analysis of Satb2 Binding in Colonic Stem Cells and Differentiated Cells

Project description:Understanding satb2 binding difference in colonic stem cells and differentiated cells

2021-10-05 | GSE180029 | GEO

Bulk RNA-seq of Epitope Expressed SATB2 in Mouse Ileum Epithelium

Project description:To investigate if Satb2 is sufficient to confer colonic fate from the small intestine mucosa, we generated a transgenic mouse line, CAGSATB2-GFP, in which CRE excision of a stop cassette activates HA epitope-tagged SATB2 and GFP fluorescence.

2021-10-05 | GSE167282 | GEO

Bulk RNA-seq of Intestine Epithelia (Jejunum, Ileum, Cecum and Colon) from Satb2-deficient and WT mice

Project description:The goal of this study is to study the consequence of Satb2 gene loss in the colonic epithelium.

2021-10-05 | GSE148692 | GEO

Bulk RNA-seq of 3D Cultured Intestinal Organoids (Ileum and Colon) from Satb2-deficient and WT mice

Project description:The colonic microenvironment may have influenced gene expression of the ileal-like mucosa in Satb2KO colon In Vivo. We use 3D culture organoid system In Vitro to mitigate the environmental influence.

2021-10-05 | GSE167281 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data