Identification of intrinsically immunogenic small cell lung carcinoma (SCLC) subpopulations

ABSTRACT: SCLC is molecularly and immunologically heterogenous. Here, using transcriptional and epigenomic profiling of plastic SCLC states in human and mouse cell lines, and patient samples, we define the phenotype of a SCLC population marked by increased MHC Class I antigen presentation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE168195 | GEO | 2021/03/04

REPOSITORIES: GEO