3D collagen-based scaffolds for biophysical tumour microenvironment studies

ABSTRACT: 3D scaffolds collagen I-based were crosslinked with different percentages of 1, 4-butanediol diglycidyl ether (BDDGE) to mimic native tissue and tumour tissue. Normal fibroblasts (NFs) or cancer-associated fibroblasts (CAFs) were added to the system to assess how mechanical features influence stromal compartment in native or tumour-like systems.

ORGANISM(S): Homo sapiens

PROVIDER: GSE168639 | GEO | 2022/01/12

REPOSITORIES: GEO