Transcript profiling of WT and SIRPα KO BMDMs post-M1 activation in the presence of mCD47.ex

ABSTRACT: To compare the inflammatory responses of WT and SIRPα KO macrophage, we performed a complete transcript profiling of WT and SIRPα-KO M1 macrophage using transcriptome sequencing as a discovery platform. SIRPα-KO mice and WT mice were kept under the same condition. BMDMs were produced from WT and SIRPα-KO mice followed by M1 polarization. RNA was then isolated from the same number of BMDMs.

ORGANISM(S): Mus musculus

PROVIDER: GSE169177 | GEO | 2021/03/19

REPOSITORIES: GEO