Transcriptome of LBR-null mouse kidneys

ABSTRACT: We tested overall gene expression change upon chromatin architecture disruption. RNA-seq was performed using nuclear architecture-disrupted mice carrying a loss-of-function mutation in LBR (Lbric-J/ic-J; LBR-null mice). LBR is an INM protein that tethers heterochromatin to the nuclear envelope whose level is decreased in various aging contexts.

ORGANISM(S): Mus musculus

PROVIDER: GSE169240 | GEO | 2021/06/01

REPOSITORIES: GEO