Transcriptional profiling of basilar artery and basilar terminus intima and media in rabbits after bilateral carotid ligation

ABSTRACT: New Zealand white rabbits underwent bilateral carotid ligation to increase flow in the basilar artery (BA) or sham surgery. 24 hours post-surgery, the BA and basilar terminus (BT) were embedded for sectioning. The intima and media were separately laser-microdissected from the sections, and whole transcriptome RNA-seq was performed on each tissue in order to more thoroughly characterize potential molecular signals between endothelium and smooth muscle during flow-induced arterial remodeling.

ORGANISM(S): Oryctolagus cuniculus

PROVIDER: GSE169276 | GEO | 2021/07/28

REPOSITORIES: GEO