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MiRNA expression profiling in early-stage epithelial ovarian cancer

ABSTRACT: Early-stage epithelial ovarian cancer (eEOC) patients have a generally favorable prognosis but heterogeneous behavior at recurrence. Accurate prediction of the risk of relapse is still a major concern, essentially to avoid overtreatment. We have identified a robust miRNA-based signature named MiROvaR able to predict early disease recurrence in case materials of mostly advanced-stage EOC patients. We challenged MiROvaR in the eEOC sub-setting (stage IA-IIB) and it proved to accurately classify eEOC patients according to their risk of relapse.

ORGANISM(S): Homo sapiens

PROVIDER: GSE169314 | GEO | 2022/12/21

REPOSITORIES: GEO

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