Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [Bulk ATAC-Seq]

ABSTRACT: ATAC-seq analysis for WT and Fli-1 KO HSPCs was performed to uncover changes in chromatin accessibility following Fli-1 deletion.

ORGANISM(S): Mus musculus

PROVIDER: GSE169397 | GEO | 2024/04/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [Bulk H3K27ac ChIP]

Project description:H3K27ac ChIP-seq analysis for WT and Fli-1 KO HSPCs was performed to uncover changes in chromatin H3K27ac modifications following Fli-1 deletion.

2024-04-01 | GSE169430 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [Bulk HSPC RNA-seq]

Project description:Presetting of adaptive hematopoiesis by Fli-1 entails reciprocal niche sensing of Notch/VEGF-A pathways to supersede Spi1-driven dormancy. RNA-seq analysis for WT and Fli-1 KO HSPCs was performed to uncover changes in transcriptional output following Fli-1 deletion.

2024-04-01 | GSE171112 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [scRNA-seq engrafted HSPCs]

Project description:Single cell RNA-seq analysis for WT and Fli-1 KO engrafted HSPCs (Lineage negative CD45.2+) was performed to assess changes in transcriptional output in HSPCs following Fli-1 deletion and Notch1 overexpression and to determine distribution of cells among the different hematopoietic populations.

2024-04-01 | GSE171113 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [snRNA/ATACseq HSPC Multiome]

Project description:Multiome single nuclei RNA/ATAC-seq analysis was performed on sorted population of SLAM LSK HSPCs to uncover transcriptional determinants regulating HSPCs in distinct transitional states.

2024-04-01 | GSE208039 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [Bulk EC RNA-seq]

Project description:RNA-seq analysis for WT and Fli-1 KO ECs was performed to assess changes in transcriptional output following Fli-1 deletion.

2024-04-01 | GSE171111 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [scRNA-seq cocultured HSPCs]

Project description:Single cell RNA-seq analysis was performed on sorted population of LSK HSPCs with different genetic background and phenotype, after co-culture with vascular niche cells, to uncover differential transcriptional output following genetic manipulation.

2024-04-01 | GSE207571 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing [CB vs mPB scRNA-seq]

Project description:Single cell RNA-seq analysis was performed on sorted population of CD45+/CD34+ HSPCs from cord blood (CB) and mobilized peripheral blood (mPB) donors, after co-culture with vascular niche cells, to uncover differential transcriptional output between HSPC derived from CB and mPB origins.

2024-04-01 | GSE208033 | GEO

Transcriptional Activation of Regenerative Haematopoiesis via Niche Sensing

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-04-01 | GSE169431 | GEO

Bulk ATAC-seq of primate cerebral organoids

Project description:Bulk ATAC-seq was performed on human, chimpanzee, bonobo, and macaque stem cell-derived cerebral organoids. ATAC-seq was performed on day 60 (2 months old) and day 120 (4 months old) cerebral organoids.

2019-10-16 | E-MTAB-8228 | biostudies-arrayexpress

Chromatin accessibility (ATAC-seq) of human acute leukemias and healthy donors

Project description:ATAC-seq of 79 primary samples obtained from human acute leukemias, namely AML, T-ALL and mixed myeloid/lymphoid leukemias with CpG Island Methylator Phenotype (CIMP). Moreover, ATAC-seq of CD34+ HSPCs from 3 healthy donors are included. ATAC-seq was performed as described (Buenrostro et al., 2013) with a modification in the lysis buffer to reduce mitochondrial DNA contamination. Due to patient confidentiality considerations, the raw data files for this dataset have been deposited to the EGA controlled-access archive under the accession numbers EGAS00001007094 (study); EGAD00001011050 (dataset).

2023-08-31 | E-MTAB-13118 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data