Weakened sarcomeric contractility distinguishes Facio Scapulo Humeral Dystrophy muscle fibers

ABSTRACT: To gain further insights into the specificity of the muscle alteration in this disease, we derived induced pluripotent stem cells from patients affected with type 1 and 2 FSHD, differentiated these cells into contractile innervated muscle fibers and analyzed their transcriptome by RNA Seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE169724 | GEO | 2022/02/18

REPOSITORIES: GEO