Identification of mRNAs enriched in G3BP immunoprecipitation

ABSTRACT: A phosphorylation-dependent endoribonuclease G3BP localizes in cytoplasmic stress granules (SGs). G3BP promotes SG assembly, oligomerizes, binds mRNA, and regulates levels of certain mRNAs. Transcripts bound to G3BP were identified through expression profiling of a total of 12,135 genes by immunoprecipitation (IP) with anti-G3BP or control IgG from S2-013 cells, converting the immunoprecipitated transcripts to cDNA by reverse transcription, and hybridizing these products to cDNA microarrays. Five G3BP-associated transcripts were identified.

ORGANISM(S): Homo sapiens

PROVIDER: GSE17056 | GEO | 2009/07/23

SECONDARY ACCESSION(S): PRJNA122685

REPOSITORIES: GEO