Global Histone H3 lysine 4 trimethylation (H3K4me3) landscape changes in response to TGF-β1

ABSTRACT: We performed Chromatin-Immunoprecipitation followed by Next-Generation Sequencing (ChIP-Seq) in PC-3 Cells stimulated with TGF-β1 for different duration. We used anti-H3K4me3 antibody to immunoprecipitate DNA fragment associated with H3K4me3. We found that a number of regions associated with H3K4me3 increased in a time-dependent manner upon TGF-β1 stimulation. Further the regions were classified into different Functional annotations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE171058 | GEO | 2021/10/27

REPOSITORIES: GEO