Transcriptomics

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Transcriptomic analysis of MYC-inhibited Medulloblastoma-derived D283 Med cells


ABSTRACT: Medulloblastoma is one of the most common malignant pediatric brain tumors. Group 3 is the most aggressive molecular subgroup, showing the highest rate of metastasis at diagnosis. To date, very few long noncoding RNAs have been implicated in Group 3 Medulloblastoma biology. Here, we identified the long noncoding RNAs dependent on the activity of the MYC oncogene, the major driver gene of Group 3 Medulloblastoma.

ORGANISM(S): Homo sapiens

PROVIDER: GSE171117 | GEO | 2021/08/11

REPOSITORIES: GEO

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