NSD2 amplifies oncogenic transcriptional output to promote lung adenocarcinoma pathogenesis [CUT&RUN]

ABSTRACT: RNA-seq of kras and kras;NSD2 driven tumor biopsies and RNA-seq and Cut-and-run of kras;NSD2 derived cells suggests NSD2 amplifies Ras-output at chromatin and separately activates oncogenic-promoting gene expression programs.

ORGANISM(S): Mus musculus

PROVIDER: GSE171216 | GEO | 2021/09/21

REPOSITORIES: GEO