Impact of 6-mercaptopurine on LPS treated primary cultures of enteric nervous system

ABSTRACT: Enteric nervous system is involved in the regulation of intestinal inflammation. We developped mouse primary cultures of enteric nervous system to study impact of LPS, as pro-inflammatory mediator, and of the pro-drug 6-mercaptopurine on enteric inflammatory pathways We used microarrays to detail the global programme of gene expression underlying enteric neuro-inflammation and identified classes of up-regulated genes during this process.

ORGANISM(S): Mus musculus

PROVIDER: GSE171308 | GEO | 2021/04/02

REPOSITORIES: GEO