Direct Immunodetection of Global A-to-I RNA Editing Activity with a Chemiluminescent Bioassay

ABSTRACT: We report the development of an ELISA-based chemiluminescent assay to measure global levels in A-to-I editing. We directly compare this performance to RNA-seq analysis using the Alu Editing Index. These attached datasets represent sequenced mRNA isolated from HEK293T cells transfected with increasing amounts of ADAR1 to induce a global increase in A-to-I RNA editing activity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE171545 | GEO | 2021/04/07

REPOSITORIES: GEO