Fine-tuned repression of Drp1 driven mitochondrial fission primes a ‘stem/progenitor-like state’ to accelerate neoplastic transformation

ABSTRACT: Mitochondria based priming of a stem/progenitor-like state involves fine-tuned repression of the master regulator of mitochondrial fission, Drp1, and drives carcinogen induced transformation in a keratinocyte model

ORGANISM(S): Homo sapiens

PROVIDER: GSE171772 | GEO | 2021/04/10

REPOSITORIES: GEO