Analysis of the differential expression of genes in Otub2- knockout mice

ABSTRACT: Oral and esophageal squamous cell carcinomas (SCCs) are associated with high mortality, yet molecular mechanisms underlying these malignancies are largely unknown. We demonstrate that epigenetic silencing of otubain 2 (OTUB2), a previously recognized oncogene, drives SSCs initiation and drug resistance.

ORGANISM(S): Mus musculus

PROVIDER: GSE171878 | GEO | 2022/09/19

REPOSITORIES: GEO