Epigenomic Regulation of Human T-Cell Leukemia Virus by Chromatin-Insulator CTCF

ABSTRACT: We compared histone modifications of wild type and HTLV-1ΔCTCF provirus by ChIP sequencing and observed that loss of the vrial CTCF binding site in HTLV-1 results in increased histone methylation 5’ and 3’ of the CTCF site, suggesting that CTCF binding may act as a boundary element to epigenetic modification.

ORGANISM(S): Human T-cell leukemia virus type I Homo sapiens

PROVIDER: GSE172194 | GEO | 2021/05/08

REPOSITORIES: GEO