Biology of human melanoma

ABSTRACT: In normal skin, interactions between melanocytes and keratinocytes, and between melanocytes and the basal membrane are functionally relevant for maintenance of homeostasis and epidermal melanin unit whose deregulation may trigger a continuous proliferation of the melanocytes. In order to further elucidate the molecular events related to cell-cell and cell-ECM interactions in relation to the biology of melanomas, we analyzed the expression profile of 64 human melanomas, 21 primary samples and 43 independent metastasis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE17275 | GEO | 2011/10/31

SECONDARY ACCESSION(S): PRJNA119137

REPOSITORIES: GEO