Circular RNA YPEL2 promotes cell proliferation, migration and invasion as a biomaker in cervical cancer

ABSTRACT: Circular RNA (circRNA) is newly type of noncoding RNA that are formed by back-splicing of exon and play the important functions in tumorigenesis. However, the research of circRNA is deficient in cervical cancer (CC). We performed high-throughput sequencing on cervical cancer tissues and normal cervical control samples. We discovered the up-regulated circYPEL2 (has_circ_0005400) in cervical cancer and used this as a potential research object through bioinformatics analysis. Finally, through RNA sequencing and bioinformatics technology, we analyzed the downstream targeted genes that may be affected by circYPEL2.

ORGANISM(S): Homo sapiens

PROVIDER: GSE173112 | GEO | 2022/01/31

REPOSITORIES: GEO