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Global characterization of prostate cancer cell expression upon treatment with media conditioned from human stromal cells epitopically expressing epiregulin (EREG)

ABSTRACT: Technical advances in next generation sequencing (NGS) has revolutionized system-based analysis of genome-wide expression, cellular pathways and responses. We performed this study to establish the transcriptomic profiles of human prostate cancer cell lines exposed to conditioned media from human primary stromal cells engineered to express epiregulin (EREG), a typical factor of the senescence-associated secretory phenotype (SASP), the latter a hallmark of senescent cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE173383 | GEO | 2022/09/30

REPOSITORIES: GEO

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MCF7 cells exposed to conditioned media from growing or senescent fibroblasts

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| PRJNA816455 | ENA

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