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MRNA expression analysis of the hippocampus in a vervet monkey model of fetal alcohol spectrum disorder

ABSTRACT: Alcohol preferring vervet dams were permitted to ingest alcohol 4 days/week during the second half of gestation (e90-e165) and paired with sucrose matched controls. Cases and controls were sacrificed with subsequent hippocampal extraction at 5 months and 2 years. RNA was extracted according to the manufacturer's protocol and hybridized to the Affymetrix Rhesus Genechip microarray. We sought to identify pathways and genes involved in the development of fetal alcohol spectrum disorder in a non-human primate in order to develop an understanding of how this disorder may develop in humans.

ORGANISM(S): Chlorocebus aethiops Macaca mulatta

PROVIDER: GSE173516 | GEO | 2022/02/23

REPOSITORIES: GEO

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