Genome-wide expression changes in response to the treatment of anti-CD93 in mouse tumor endothelial cells

ABSTRACT: We isolated ECs from anti-CD93 antibody treated or control KPC tumor and performed RNA-seq to investigate genome-wide expression changes in response to the treatment of anti-CD93. Many of the genes affected by anti-CD93 were functionally related to cell adhesion, angiogenesis or vasculature development. Gene ontology analysis further confirmed that the transcriptomic changes by anti-CD93 were mainly related to biological pathways of angiogenesis, cell adhesion, or vasculature development.

ORGANISM(S): Mus musculus

PROVIDER: GSE173658 | GEO | 2021/05/01

REPOSITORIES: GEO